If you’re looking for the spider killer spray for indoors you’re in the right place. We spent a lot of time reviewing best spider killer spray for indoors to come up with the Ten that we think stand apart from the pack in style, functionality, and value. In this guide, we have reviewed all the products and generated the best options available today for you.
We analyzed and compared 40 spider killer spray for indoors sold for nearly 40 hours, and considered the opinions of 650 consumers. Following our last update, our favorite model is the Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen). However, if you don’t want to spend extra then we have another vast option for you is TERRO T401SR Indoor and Outdoor Ant Killer Aerosol Spray – Kills Ants, Cockroaches, Crickets, Scorpions, Spiders, and Other Insects – 2 Pack 32 Total Ounces.
Below is a review of some of the best spider killer spray for indoors together with their extra features and functions. Wanna find the Top spider killer spray for indoors? Read the below list right the way.
Best spider killer spray for indoors

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Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)
Features
- FAST KNOCKDOWN: Kills listed insects on contact* and keeps killing up to 3 months.**
- KILLS INSECTS INDOORS: Hot Shot Ant, Roach & Spider Killer kills ants, cockroaches, spiders, fleas, silverfish, firebrats, crickets, Asian ladybeetles, carpet beetles, waterbugs, palmetto bugs and stink bugs indoors.
- KILLS INSECTS OUTDOORS: This product kills ants, cockroaches, spiders, fleas, crickets, Asian ladybeetles, stink bugs, palmetto bugs and waterbugs outdoors.
- CRISP LINEN SCENT: Use Hot Shot Ant, Roach & Spider Killer to kill insects while leaving behind a crisp linen scent.
- NO OILY RESIDUE: Spray surface until damp; this product leaves no oily residue behind.
Ortho Home Defense Insect Killer for Indoor & Perimeter2 with Comfort Wand, Controls Ants, Roaches, and Spiders, 1.1 gal
Features
- Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a bug killer spray that kills the toughest home invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish, and periodical cicadas (as listed)
- Provides a long-lasting bug barrier of up to 12 month protection (against ants, roaches, and spiders indoors on non-porous surfaces)
- Apply this pesticide anytime as a preventative treatment or after you see evidence of insect activity
- Use this pest control spray with confidence indoors (kitchens, bathrooms, doors and windows) and outdoors (perimeter of foundations, patios and decks, garages) wherever insects are a recurring problem
- The easy-to-use continuous spray Comfort Wand helps you control insects easily and accurately without any bending, pumping, or hand-fatigue
Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 32 fl Ounce Ready-To-Use Spray
Features
- HOME BARRIER: Indoor plus outdoor insect control.
- KILLS ON CONTACT: Up to 12 months of control for cockroaches on non-porous surfaces — also kills ants, roaches, spiders, fleas, ticks and other listed insects.
- NON-STAINING: Water-based, clear formula leaves no odor or oily residue.
- READY TO USE: No mixing required.
TERRO T401SR Indoor and Outdoor Ant Killer Aerosol Spray – Kills Ants, Cockroaches, Crickets, Scorpions, Spiders, and Other Insects – 2 Pack 32 Total Ounces
Features
- 2 bottles included
- Kills ants and other insects on contact
- Kills on contact and continues to kill for up to 6 weeks
- Use as a spot treatment and in cracks and crevices
- 16 oz aerosol can with twist-to-open top
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
Features
- Start killing ants, roaches, spiders, fleas and ticks with Ortho Home Defense Max Indoor Insect Barrier
- This insect control spray kills listed bugs and protects your home for 365 days against ants, roaches and spiders indoors on nonporous surfaces
- Use this indoor insect spray in kitchens, bathrooms and basements, and around doors and windows; apply outdoors to foundations to create a barrier around your home
- Create an insect barrier anytime as a preventative treatment or after you see evidence of insect activity
- Apply Ortho Home Defense Max Indoor Insect Barrier using the Extended Reach Comfort Wand, which lets you spray without bending
Stem Kills Ants, Roaches And Spiders: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 10 fl oz (Pack Of 1)
Features
- Bug spray that quickly kills ants, roaches and spiders
- Plant-based active ingredient bug killer safe for use around people and pets (when used as directed)
- Entomologist-tested bug spray made with botanical extracts to kill bugs; with a fresh scent and no added dye, fragrance, or harsh chemical odors
- Bug killer for indoor and outdoor use, wherever bugs try to bother you
- Rooted in Nature, Optimized by Science
Wet & Forget 803064 Miss Muffet’s Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64 Fluid Ounces, Ready to Use
Features
- Kills spiders and creates a barrier inside and outside the home to keep them away for up to 12 months with just one application
- Attached sprayer for quick and easy application with a spray range of up to 10 feet for those hard to reach places
- Treat all areas were spiders are found, spray until wet but not soaking and for long lasting results leave spray undisturbed
- Apply in calm weather where rain is not expected for 24hrs and allow to dry completely before entering treated area
- Miss Muffet's Revenge is ready to use and specially formulated for all spiders except Black Widow and Brown Recluse
Mighty Mint – 16oz Spider Repellent Peppermint Oil – Natural Spray for Spiders and Insects – Killer + Deterrent
Features
- PET-FRIENDLY & FAMILY-SAFE FORMULA – Mighty Mint is a top pick for pet parents looking for a natural pest control solution. Safe to use around dogs, cats, and kids when applied as directed—no harsh fumes or dangerous chemicals, just powerful peppermint protection you can trust.
- POWERFUL PLANT-BASED PEST CONTROL – Formulated with extra-concentrated peppermint oil and geraniol, this spray quicky repels and kills ants on contact using a proven natural formula. Effective on carpenter and sugar ants.
- EFFECTIVE INDOOR & OUTDOOR USE – Designed for versatile application on baseboards, entryways, patios, and other areas. Helps repel insects from kitchens, bathrooms, living spaces, and more—without staining surfaces.
- FRESH MINTY SCENT WITH LONG-LASTING EFFECT – Infused with pure peppermint oil, this formula leaves a crisp, clean aroma that lingers without overwhelming. Free from synthetic fragrances and common allergens, making it a gentle option for scent-sensitive households.
- READY-TO-USE 16 OZ SPRAY FOR TARGETED APPLICATION – Perfect for quick treatments in high-traffic areas, this 16 oz bottle delivers fast, focused pest control against spiders, ants, and other common insects. Pre-mixed and easy to use—just spray and go for natural protection wherever it’s needed most.
This guide identifies some of the best spider killer spray for indoors currently on the market and also includes an in-depth buying guide to help you make the right decision. If you didn’t find your desired one check out the Wet & Forget 803064 Miss Muffet’s Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64 Fluid Ounces, Ready to Use is also the most sold item in the market. If you feel that the information provided here is misleading, incorrect, or is removed from actual facts, then please do not hesitate to get in touch with us. We will always be there for you.







