If you’re looking for the mice for large hands you’re in the right place. We spent a lot of time reviewing best mice for large hands to come up with the Ten that we think stand apart from the pack in style, functionality, and value. In this guide, we have reviewed all the products and generated the best options available today for you.
We analyzed and compared 38 mice for large hands sold for nearly 38 hours, and considered the opinions of 587 consumers. Following our last update, our favorite model is the Logitech Wireless Mouse M190 – Full Size Ambidextrous Curve Design, 18-Month Battery with Power Saving Mode, Precise Cursor Control & Scrolling, Wide Scroll Wheel, Thumb Grips – Mid Grey. However, if you don’t want to spend extra then we have another vast option for you is Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook – Black.
Below is a review of some of the best mice for large hands together with their extra features and functions. Wanna find the Top mice for large hands? Read the below list right the way.
Best mice for large hands
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Product Title
Score
Logitech Signature M550 L Full Size Wireless Mouse – for Large Sized Hands, 2-Year Battery, Silent Clicks, Bluetooth, Multi-Device Compatibility – Black
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9.8
E-YOOSO Large Wireless Mouse for Big Hands, X-31 Cordless Ergo Computer Mouse, 6 Buttons, 5-Level 4800 DPI, 18 Months Battery Life, for Laptop, PC, Chromebook (Black)
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9.6
Logitech Wireless Mouse Signature M650 L Full Size – Large Hands, 2-Year Battery, Silent Clicks, Customizable Buttons, Bluetooth, PC/Mac/Chromebook – Black, Right-Handed, Large
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9.3
Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook – Black
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8.8
Logitech Wireless Mouse M190 – Full Size Ambidextrous Curve Design, 18-Month Battery with Power Saving Mode, Precise Cursor Control & Scrolling, Wide Scroll Wheel, Thumb Grips – Mid Grey
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8.3
Logitech G502 HERO High Performance Wired Gaming Mouse, HERO 25K Sensor, 25,600 DPI, RGB, Adjustable Weights, 11 Programmable Buttons, On-Board Memory, PC / Mac
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8.2
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC – Graphite
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7.6
Logitech MX Master 2S Bluetooth Edition Wireless Mouse – Use on Any Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Control Up to 3 Apple Mac and Windows Computers – Graphite
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7.5
Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
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7.3
Lekvey Ergonomic Mouse, Vertical Wireless Mouse – Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
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6.9
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Product Title
9.8
Logitech Signature M550 L Full Size Wireless Mouse – for Large Sized Hands, 2-Year Battery, Silent Clicks, Bluetooth, Multi-Device Compatibility – Black
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9.6
E-YOOSO Large Wireless Mouse for Big Hands, X-31 Cordless Ergo Computer Mouse, 6 Buttons, 5-Level 4800 DPI, 18 Months Battery Life, for Laptop, PC, Chromebook (Black)
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9.3
Logitech Wireless Mouse Signature M650 L Full Size – Large Hands, 2-Year Battery, Silent Clicks, Customizable Buttons, Bluetooth, PC/Mac/Chromebook – Black, Right-Handed, Large
Buy Now
Buy Now
8.8
Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook – Black
Buy Now
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8.3
Logitech Wireless Mouse M190 – Full Size Ambidextrous Curve Design, 18-Month Battery with Power Saving Mode, Precise Cursor Control & Scrolling, Wide Scroll Wheel, Thumb Grips – Mid Grey
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8.2
Logitech G502 HERO High Performance Wired Gaming Mouse, HERO 25K Sensor, 25,600 DPI, RGB, Adjustable Weights, 11 Programmable Buttons, On-Board Memory, PC / Mac
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7.6
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC – Graphite
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7.5
Logitech MX Master 2S Bluetooth Edition Wireless Mouse – Use on Any Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Control Up to 3 Apple Mac and Windows Computers – Graphite
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7.3
Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
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6.9
Lekvey Ergonomic Mouse, Vertical Wireless Mouse – Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
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Logitech Signature M550 L Full Size Wireless Mouse – for Large Sized Hands, 2-Year Battery, Silent Clicks, Bluetooth, Multi-Device Compatibility – Black
Logitech Signature M550 L Full Size Wireless Mouse - for Large Sized Hands, 2-Year Battery, Silent Clicks, Bluetooth, Multi-Device Compatibility - Black
$21.00 in stock
2 new from $21.00
6 used from $18.84
6 used from $18.84
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Scroll smarter: With Logitech Signature M550 Wireless Mouse you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
- The optimal fit for your hand: This comfortable full size mouse is designed for larger hands, for the optimal fit
- Upgrade your comfort: This work mouse provides long hours of comfort thanks to a contoured shape, soft thumb area, and rubber side grips that keep your hand snug and in place
- Connect the way you like: Connect this cordless computer mouse in an instant via Bluetooth Low Energy or Logi Bolt USB receiver
- Less noise, more focus: Whether working at the office or at home, Logitech Signature M550 is a quiet mouse, allowing you to enjoy 90 percent less click noise with SilentTouch technology*
E-YOOSO Large Wireless Mouse for Big Hands, X-31 Cordless Ergo Computer Mouse, 6 Buttons, 5-Level 4800 DPI, 18 Months Battery Life, for Laptop, PC, Chromebook (Black)
E-YOOSO Large Wireless Mouse for Big Hands, X-31 Cordless Ergo Computer Mouse, 6 Buttons, 5-Level 4800 DPI, 18 Months Battery Life, for Laptop, PC, Chromebook (Black)
$16.99 in stock
2 used from $17.21
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- 【Anti-Sweat & Ergonomic Design】E-YOOSO Large Mouse is made of anti-slip and anti-sweat custom material, built with a comfortable contoured shape that naturally fits big hands. The finger rests on both sides of the mouse provide additional support, every finger can hold comfortably for a long time. X-31 large mouse adopts a large size design, and also has forward and backward buttons, make your web surfing more efficient, perfect performance for more than 50,000,000 keystrokes!
- 【5-Level 4800 DPI & 2 Kinds Polling Rate】5-level DPI settings (800/1200(default)/1600/2000/4800), choose your comfortable speed for working. X-31 will move more precise by 125Hz(default) or 250Hz polling rate: Press the right button + the middle buttom for 3 seconds to switch polling rate.
- 【USB Plug And Play & Stable Cursor】USB Nano Receiver can be stored within the back of the mouse, plug and play. 2.4GHz Wireless technology provides reliable connection, transmission distance up to 33ft (10m), which eliminated delays, interference, and provided a fast data transmission.
- 【18 Months Battery Life & Power Saving Mode】X-31 Large wireless mouse with 18 months battery life. The X-31 mouse with smart auto sleep mode. If the mouse is not used for 8 minutes, it will automatically enter the dormant state to save power, and click the mouse again to run.
- 【Universal Compatibility & Wide Use】 Large wireless optical MacBook mouse is compatible with Windows 11, 10, 8.1, 8, 7, XP, Vista, Linux, Chromebook, Mac OS(Side buttons are not available on Mac), Surface Pro, Surface, and Any Device with USB Ports. As well as compatible for PC, Laptop, MacBook and more.
Logitech Wireless Mouse Signature M650 L Full Size – Large Hands, 2-Year Battery, Silent Clicks, Customizable Buttons, Bluetooth, PC/Mac/Chromebook – Black, Right-Handed, Large
Logitech Wireless Mouse Signature M650 L Full Size - Large Hands, 2-Year Battery, Silent Clicks, Customizable Buttons, Bluetooth, PC/Mac/Chromebook - Black, Right-Handed, Large
$36.99 in stock
3 new from $36.99
4 used from $24.37
4 used from $24.37
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Connect the way you like: Connect this Logitech mouse wireless in an instant via Bluetooth Low Energy or Logi Bolt USB receiver, suitable as a wireless mouse for Chromebook, PC, and Mac
- Customizable side buttons: Customize the side buttons on the wireless mouse Logitech with Logitech Options+; available on Windows and macOS, to your favorite shortcuts – like back/forward, or copy/paste.
- Scroll smarter: With Logitech Signature M650 Wireless Mouse for PC, you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
- Upgrade your comfort: This wireless mouse with side buttons provides long hours of comfort thanks to its shape, soft thumb area, and rubber side grips that keep your hand snug. Sizes and handedness available.
- Less noise, more focus: Whether working at the office or at home, Logitech Signature M650 is a silent wireless mouse, allowing you to enjoy 90 percent less click noise with SilentTouch technology.
Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook – Black
Logitech M705 Marathon Wireless Mouse, 2.4 GHz USB Unifying Receiver, 1000 DPI, 5-Programmable Buttons, 3-Year Battery, Compatible with PC, Mac, Laptop, Chromebook - Black
$34.99 in stock
3 used from $20.35
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Multi-Device Wireless Mouse: Move cursor, text, and files across multiple computers with Logitech FLOW; With this wireless Bluetooth mouse for laptop and PC, you can easily switch between up to 3 computers or laptops with the touch of a button
- Hyper-Fast Scrolling: Fly through long documents and web pages with a simple spin of the mouse wheel, featuring an additional instant-stop option with this Logitech wireless mouse
- Dual Connectivity: Connect this Bluetooth wireless mouse via the Logitech Unifying Receiver, which allows you to connect up to 6 compatible Logitech peripherals to this wireless computer mouse with just one USB receiver
- Comfortable Grip: Crafted for the right hand, this full-sized Logitech mouse wireless features a rubber body and a sculpted design for palm rest grip and comfort like never before
- Long-lasting and Versatile: Designed for endurance with 36-month battery life (1), M705 is a Logitech bluetooth mouse compatible with computers, laptops, tablets, Windows, macOS, Chrome OS, Linux, and iPadOS.
Logitech Wireless Mouse M190 – Full Size Ambidextrous Curve Design, 18-Month Battery with Power Saving Mode, Precise Cursor Control & Scrolling, Wide Scroll Wheel, Thumb Grips – Mid Grey
Logitech Wireless Mouse M190 - Full Size Ambidextrous Curve Design, 18-Month Battery with Power Saving Mode, Precise Cursor Control & Scrolling, Wide Scroll Wheel, Thumb Grips - Mid Grey
$14.10 in stock
4 used from $8.58
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- CORDLESS COMFORT: The mouse is crafted with a contoured, ergonomic shape that follows the natural curve of larger hands and guides fingers into ideal placement with scooped buttons for all-day comfort
- LAG-FREE WIRELESS CONNECTION – Work wirelessly and move freely – from up to 10 meters away – with virtually no delays or dropouts. No cable means no clutter on your desk and easy transporting
- HIGH-QUALITY PRECISION: Don’t compromise on quality with work or gaming. Precision tracking, line-by-line scrolling and simple navigation mean you can say goodbye to annoying missed clicks
- BUILT TO LAST: Designed by the number one world leader in mice and keyboards, the M190 is an everyday laptop and PC computer mouse you can depend on. It’s durable, reliable, and built to last
- LONG-LASTING BATTERY: Enjoy up to 18 months of worry-free usage thanks to a long-lasting battery, and a mouse that kicks into power saving mode automatically when not in use. AA Battery is included
Logitech G502 HERO High Performance Wired Gaming Mouse, HERO 25K Sensor, 25,600 DPI, RGB, Adjustable Weights, 11 Programmable Buttons, On-Board Memory, PC / Mac
Logitech G502 HERO High Performance Wired Gaming Mouse, HERO 25K Sensor, 25,600 DPI, RGB, Adjustable Weights, 11 Programmable Buttons, On-Board Memory, PC / Mac
$42.07 in stock
14 new from $41.99
9 used from $37.85
9 used from $37.85
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Hero 25K sensor through a software update from G HUB, this upgrade is free to all players: this Logitech gaming mouse has 1:1 tracking, 400-plus ips, 100 - 25,600 dpi plus zero smoothing, filtering, or acceleration.
- Adjustable weight system: Arrange up to five removable 3.6 grams weights inside the gaming mouse for personalized weight and balance tuning.
- Mechanical switch button tensioning: Metal spring tensioning system and pivot hinges are built into left and right gaming mouse buttons for a crisp, clean click feel with rapid click feedback with this black gaming mouse
- 11 customizable buttons and onboard memory: Assign custom commands to the buttons and save up to five ready to play profiles directly to the wired mouse. Suitable for pc gaming mouse needs.
- Programmable RGB Lighting and Lightsync technology: Customize lighting from nearly 16.8 million colors to match your team's colors or sync colors with other Logitech G gear on this wired mouse for gaming
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC – Graphite
Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC - Graphite
$79.99 in stock
5 new from $69.00
18 used from $53.68
18 used from $53.68
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Lift yourself up: When desk work gets you down, lift yourself up with this Logitech Wireless Ergonomic Mouse - a great fit for small to medium right hands
- Raise your hand into comfort with this computer mouse wireless: Rest on Lift upright mouse throughout the day with a softly textured grip and snug thumb rest for level-above coziness
- 57 degrees of soothe: This wireless ergonomic mouse promotes a more natural posture in the forearm for comfort and productivity, for day-long comfort and productivity
- Relax into focus: Settle into work with this ergonomic wireless mouse featuring easy-to-reach customizable buttons, whisper-quiet clicks, and a SmartWheel for smooth, seamless scrolling
- Ergo-certified: This wireless vertical mouse has been designed, developed, tested, and approved according to criteria set out by leading ergonomists
Logitech MX Master 2S Bluetooth Edition Wireless Mouse – Use on Any Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Control Up to 3 Apple Mac and Windows Computers – Graphite
Logitech MX Master 2S Bluetooth Edition Wireless Mouse – Use on Any Surface, Hyper-Fast Scrolling, Ergonomic, Rechargeable, Control Up to 3 Apple Mac and Windows Computers - Graphite
$69.99 in stock
3 used from $51.32
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- With Logitech Flow, seamlessly control up to three computers with one mouse and copy-paste text, images and files between them.(1)
- Darkfield High Precision tracking gives you flawless control virtually anywhere – even on glass(2) with up to 4,000 DPI
- Just plug MX Master 2S into your computer using the micro-USB charging cable and get enough power for a full day of usage in three minutes only. A full charge can last up to 70 days.(3)
- Scroll through long documents or web pages faster and easier with the speed-adaptive scroll wheel that auto-shifts from click-to-click to hyper-fast scroll and side-to-side scrolling with a stroke of your thumb.(4)
- The perfectly crafted, hand-sculpted shape (5) supports your hand and wrist in a comfortable, natural position. Enjoy fine-motion control and a fluid experience thanks to well-positioned buttons and wheels.
Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
Logitech MX Vertical Wireless Mouse – Ergonomic Design Reduces Muscle Strain, Move Content Between 3 Windows and Apple Computers, Rechargeable, Graphite
$119.00 in stock
16 new from $119.00
19 used from $63.71
19 used from $63.71
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Logitech MX Vertical Wireless Ergonomic Mouse is a great fit for medium to large size right hands
- NATURAL HANDSHAKE POSITION: MX Vertical’s natural handshake position reduces muscular activity by 10 percent compared to a standard mouse – without any loss in overall performance
- 57° VERTICAL ANGLE FOR IMPROVED WRIST POSTURE: MX Vertical’s unique 57° vertical angle reduces the pressure on your wrist, while your thumb is positioned comfortably on the thumb rest
- USER TESTED. ERGONOMIST-APPROVED: MX Vertical has been designed and tested with criteria set out by leading ergonomists – improve posture, lower muscle strain, and reduce wrist pressure
- ADVANCED OPTICAL TRACKING WITH CURSOR SPEED SWITCH: The 4000 DPI high-precision sensor results in 4x less hand movement and reduces fatigue. The cursor speed switch instantly adjusts DPI speed and accuracy with the touch of a button
Lekvey Ergonomic Mouse, Vertical Wireless Mouse – Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
Lekvey Ergonomic Mouse, Vertical Wireless Mouse - Rechargeable 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels 6 Buttons, for Laptop, PC, Computer, Desktop, Notebook etc, Black
$24.99 in stock
8 new from $24.99
Free shipping
Amazon.com
as of June 9, 2025 8:18 pm
Features
- Ergonomic, Sleek and Rechargeable Design: Scientific ergonomic design encourages healthy neutral " handshake " wrist and arm positions for smoother movement and less overall strain
- Multifunction and Convenient: Advanced " Page Back " and " Page Forward " functionality buttons provide convenience when web page browsing. 800 /1200/1600 DPI Levels -- Easily adjusts the sensitivity of the mouse
- High-Capacity Rechargeable Battery: Built-in rechargeable battery. You no longer need to buy batteries, very convenient !! Easy To Use -- One nano USB receiver at the bottom of the mouse, Just Plug and Play
- Widely Compatible: Widely compatible with Windows 2000 / XP / Vista / 7 / 8 / 10 / Linux. ** Note: Not compatible with Mac OS, Apple Products. ** Once you get used to the ergonomic mouse, you will love it so much
- Lekvey Wireless Ergonomic Mouse: Revolutionize your work experience! Are you tired of using traditional mice that strain your wrist? Say goodbye to discomfort and hello to the Lekvey wireless carpal tunnel mouse! Designed with your ergonomic needs in mind, this innovative vertical ergonomic mouse offers a whole different level of comfort and efficiency
This guide identifies some of the best mice for large hands currently on the market and also includes an in-depth buying guide to help you make the right decision. If you didn’t find your desired one check out the Logitech Lift Vertical Ergonomic Mouse, Wireless Bluetooth or USB Receiver, Quiet Clicks, 4 Buttons, Right Hand Wireless Mouse, Windows/macOS/iPadOS, Laptop, PC – Graphite is also the most sold item in the market. If you feel that the information provided here is misleading, incorrect, or is removed from actual facts, then please do not hesitate to get in touch with us. We will always be there for you.
